Home  >  Products  >  CD61 (BDPLT2, GT, Integrin beta 3 (Platelet Glycoprotein IIIa, Antigen CD61), Integrin beta-3, ITGB3, Platelet Membrane Glycoprotein IIIa, GP3A, GPIIIa)
CD61 (BDPLT2, GT, Integrin beta 3 (Platelet Glycoprotein IIIa, Antigen CD61), Integrin beta-3, ITGB3, Platelet Membrane Glycoprotein IIIa, GP3A, GPIIIa)

CD61 (BDPLT2, GT, Integrin beta 3 (Platelet Glycoprotein IIIa, Antigen CD61), Integrin beta-3, ITGB3, Platelet Membrane Glycoprotein IIIa, GP3A, GPIIIa)

Cat no: C2414-18

Supplier: United States Biological
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CD61 is expressed on megakaryocytes, platelets and their precursors. It functions in platelet aggregation and is also a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectin. This antibody will help detect CD61 and be a marker for platelets and megakaryocytes in normal and uncharacterized tissues. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 1:50-1:100 for 1 hr. at RT Optimal dilutions to be determined by the researcher. Positive Control: Tonsil (staining pattern platelets) Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2414-18
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 1ml
Form: Supplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.
P type: Mab
Isotype: IgG1
Purity: Supernatant
References: 1.Von dem Borne A E G, Modderman P W, Admiral L G, et al.. Platelet antibodies, the overall results. In Knapp W, et al. eds. Leukocyte Typing IV. Oxford University Press: 951-966 (1989). 2.Gatter K C, Cordeil J L, Turley H, et al.. The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens. Histopathology. 13:257-267 (1988). 3.Zimrin A B, Eisman R, Vilaire G, et al.. Structure of platelet glycoprotein IIIa. A common subunit for two different membrane receptors. J Clin Invest. 81:1470-1475 (1988). 4.Vainchenker W, Deschamps J F, Bastin J M, et al.. Two monoclonal antiplatelet antibodies as markers of human megakaryocyte maturation: immunofluorescent staining and platelet peroxidase detection in megakaryocyte colonies and in in vivo cells from normal and leukemic patients. Blood. 59:514-521 (1982).
Additional info: Recognizes CD61. Species Crossreactivity: Human.

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