CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51.
CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.
Applications:
Suitable for use in Flow Cytometry. Other applications not tested.
Recommended Dilution:
Flow Cytometry: 1:100-1:200 Use 10ul of the suggested working dilution to label 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher.
Hybridoma:
Spleen cells from immunized Balb/c mice were fused with cells of the NS1 myeloma cell line.
Recommended Secondary Antibodies
I1904-65W: IgG, F(ab