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CD61 (Glycoprotein IIIa, Integrin beta3)

Cat no: C2414-02F


Supplier: United States Biological
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CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:100-1:200 Use 10ul of the suggested working dilution to label 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Hybridoma: Spleen cells from immunized Balb/c mice were fused with cells of the NS1 myeloma cell line. Recommended Secondary Antibodies I1904-65W: IgG, F(ab
Catalogue number: C2414-02F
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, pH7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Alternative names: Integrin Beta 3 chain
References: 1. Phillips, D.R. et al. (1991) Cell 65:359-362. 2. Hynes, R.O. (1992) Cell 69:11-25. 3. Michelson, A. D. et al. (1995) Leucocyte Typing V. Oxford University Press p 1230-1231. 4. Gatter, K. et al. (1998) Histopathology 13:257-267.
Additional info: Recognizes human CD61, a 105kD glycoprotein, which is also known as integrin beta 3 chain.

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