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CD61 (Integrin beta 3 (Platelet Glycoprotein IIIa, Antigen CD61), Integrin beta-3, ITGB3, Platelet Membrane Glycoprotein IIIa, GP3A, GPIIIa)

Cat no: C2414-21H


Supplier: United States Biological
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CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. Applications: Suitable for use in Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: frozen Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 1ml ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2414-21H
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry
Size: 1ml
Form: Supplied as a lyophilized powder in PBS, sodium azide. Reconstitute with 1ml ddH2O.
P type: Mab
Isotype: IgG1,k
Purity: Purified by ammonium sulfate precipitation and DEAE chromatography.
Alternative names: Platelet glycoprotein IIIa, ITGB3, GP3A
References: 1. Khaspekova, et al., 1993, Br. J. Haematol. 85, 332-340. 2. Mazurov, A., et al., 1995, Thromb. Haemost. 73, 1194 (abstract).
Additional info: Recognizes CD61, preferentially with the activated/occupied form of platelet GPIIb-IIIa (ligand- induced biding site or LIBS epitope) and dissociated form of GPIIIa.

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