Home  >  Products  >  CD62P (P-Selectin, CD62 Antigen-like Family Member P, Granule Membrane Protein 140, GMP-140, Leukocyte-endothelial Cell Adhesion Molecule 3, LECAM3, Platelet Activation Dependent Granule-external Membrane Protein, PADGEM, SELP, GMRP, GRMP)
CD62P (P-Selectin, CD62 Antigen-like Family Member P, Granule Membrane Protein 140, GMP-140, Leukocyte-endothelial Cell Adhesion Molecule 3, LECAM3, Platelet Activation Dependent Granule-external Membrane Protein, PADGEM, SELP, GMRP, GRMP)

CD62P (P-Selectin, CD62 Antigen-like Family Member P, Granule Membrane Protein 140, GMP-140, Leukocyte-endothelial Cell Adhesion Molecule 3, LECAM3, Platelet Activation Dependent Granule-external Membrane Protein, PADGEM, SELP, GMRP, GRMP)

Cat no: C2415-55Z

Supplier: United States Biological
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CD62P is a 140 kD type I transmembrane glycoprotein also known as P-Selectin, platelet activation-dependent granule membrane protein (PADGEM), or GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells. CD62 is primarily stored in secretory a-granules in platelets and Weibel-Palade bodies in endothelial cells and is rapidly relocated to the plasma membrane upon activation. The ligands for CD62P are CD162 and CD24. A primary function of CD62P is cell adhesion during neutrophil rolling, platelet-neutrophil, and platelet-monocyte interactions. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2415-55Z
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Skinner, M., et al. 1991. J. Biol. Chem. 266:5371. 2. Kishimoto, T. , et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London. 3. Yen, Y-T., et al. 2006. J. Virolo. 80:2684. 4. McEver, R., et al. 1995. J. Biol. Chem. 270:11025. 5. Varki, A. 1994. PNAS 91:7390.
Additional info: Recognizes human CD62P. Species Crossreactivity: chimpanzee.

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