Home  >  Products  >  CD63 (CD63 Antigen, Granulophysin, Lysosome-associated Membrane Glycoprotein 3, LAMP-3, ME491, Melanoma 1 Antigen, MLA1, Melanoma-associated Antigen ME491, MGC72893, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)

CD63 (CD63 Antigen, Granulophysin, Lysosome-associated Membrane Glycoprotein 3, LAMP-3, ME491, Melanoma 1 Antigen, MLA1, Melanoma-associated Antigen ME491, MGC72893, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)

Cat no: C2418-03


Supplier: United States Biological
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CD63 is a lysosomal granule-membrane glycoprotein and has been detected on the surface and in the cytoplasma of a variety of cells, particularly in platelets; surface expression indicates lysosomal secretion. CD63, present only in azurophil granules of non-stimulated neutrophils, is strongly expressed at the surface of neutrophils after activation showing that CD63 is a good marker for granule release; this phenomenon has been also reported for basophils. CD63 is present in cell line PHA blasts, K562, U937, KG1a, RAJI. Both surface and cytoplasmic reactions are reported. CD63 antigen has a diverse distribution on the surface and in the cytoplasm of many cell types including lymphoid, myeloid, endothelial cells and melanoma. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:10-1:25. 10ul labels 10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2418-03
Reactivities: Bovine
Hosts: Mouse
Applications: Flow Cytometry
Size: 250ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Alternative names: CD63 Molecule, Lysosome-associated Membrane Protein 3, LAMP 3, LAMP3, Mast Cell Antigen AD1, Melanoma-associated Antigen ME491, Melanoma-associated Antigen MLA1
Additional info: Recognizes the bovine homologue of the cell surface glycoprotein CD63.

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