Home  >  Products  >  CD63 (CD63 Antigen, Granulophysin, Lysosome-associated Membrane Glycoprotein 3, LAMP-3, ME491, Melanoma 1 Antigen, MLA1, Melanoma-associated Antigen ME491, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)
CD63 (CD63 Antigen, Granulophysin, Lysosome-associated Membrane Glycoprotein 3, LAMP-3, ME491, Melanoma 1 Antigen, MLA1, Melanoma-associated Antigen ME491, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)

CD63 (CD63 Antigen, Granulophysin, Lysosome-associated Membrane Glycoprotein 3, LAMP-3, ME491, Melanoma 1 Antigen, MLA1, Melanoma-associated Antigen ME491, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)

Cat no: C2418-03C

Supplier: United States Biological
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The CD63 antigen (Melanoma 1 antigen) is a glycoprotein of 40-60kD belonging to the tetraspans family (TM4SF). CD63 is intracellular lysosomal/endosomal/granule protein that is translocated to cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker). CD63 is also expressed on monocytes/macrophages and endothelium. Its cellular function has not been exactly elucidated. CD63 is thought to be associated with the early stages of melanoma tumor progression (in regulation of motility and adhesion of melanoma cells). Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Detection of activated platelets, neutrophils and basophils. Other applications not tested. Recommended Dilutions: Western Blot: Non-reducing conditions Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2418-03C
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Alternative names: CD63 Molecule, Lysosome-associated Membrane Protein 3, LAMP 3, LAMP3, Mast Cell Antigen AD1, Melanoma-associated Antigen ME491, Melanoma-associated Antigen MLA1, MGC72893
Additional info: Recognizes human CD63.

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