Home  >  Products  >  CD64 (High Affinity Immunoglobulin gamma Fc Receptor I, IgG Fc Receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, FCGR1A, FCG1, FCGR1, IGFR1)
CD64 (High Affinity Immunoglobulin gamma Fc Receptor I, IgG Fc Receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, FCGR1A, FCG1, FCGR1, IGFR1)

CD64 (High Affinity Immunoglobulin gamma Fc Receptor I, IgG Fc Receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, FCGR1A, FCG1, FCGR1, IGFR1)

Cat no: C2419-05Q

Supplier: United States Biological
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CD64 is a 72kD single chain type I glycoprotein also known as FcgRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-g stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC). Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)1ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2419-05Q
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. McMichael, A., et al., Eds. 1987. Leucocyte Typing III. Oxford University Press. New York. 2. Schlossman, S., et al., Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. 3. Kishimoto, T., et al., Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London. 4. van Tits, L., et al., 2005. Arterioscler Thromb Vasc Biol. 25: 717. 5. Holl, V., et al., 2004. J. Immunol. 173:6274. 6. Hober, D., et al., 2002. J. Gen. Virol. 83:2169. 7. Cho, H., et al., 2007. Physiol Genomics doi:10.1152/physiolgenomics.00051.2006
Additional info: Recognizes human CD64.

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