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CD68 Monoclonal Antibody

Cat no: ABM40050

CD68 Monoclonal Antibody

CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. CD68 molecule primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. CD68 molecule is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

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SPECIFICATIONS

Catalog Number

ABM40050

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Gene Id

968

Isotype

Mouse IgG1

Accession

P34810

Clonality

Monoclonal

Concentration

1 mg/ml

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