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CD69 (Early Activation Antigen CD69, 5830438K24Rik, AI452015, AIM, VEA)

CD69 (Early Activation Antigen CD69, 5830438K24Rik, AI452015, AIM, VEA)

Cat no: C2424-11G

Supplier: United States Biological
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CD69 is a 60kD type II membrane protein composed of a 27/33kD disulfide-linked homodimer, also known as Very Early Activation Antigen (VEA), AIM, EA1, MLR3 and gp34/28. It is expressed on a subset of thymocytes and platelets. CD69 is rapidly induced on activated T and B cells, neutrophils, and NK cells. It is a C-type lectin, closely related to the NKR-P1 and Ly-49 NK cell activation molecules. CD69 is involved in the early events of cell activation and thymocyte positive selection. This antibody has been reported to augment T cell activation. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, Immunofluorescence and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)1ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2424-11G
Reactivities: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Size: 500ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Testi R, et al. 1994. Immunol. Today 15:479. 3. Moretta A, et al. 1991. J. Exp. Med. 174:1393. 4. Yokoyama WM, et al. 1988. J. Immunol. 141:369.
Additional info: Recognizes mouse CD69.

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