Home  >  Products  >  CD70 (CD27L, CD27-L, CD27LG, CD27 ligand, CD70 antigen, TNFSF7, Tumor necrosis factor ligand superfamily member 7

CD70 (CD27L, CD27-L, CD27LG, CD27 ligand, CD70 antigen, TNFSF7, Tumor necrosis factor ligand superfamily member 7

Cat no: C2425-01B


Supplier: United States Biological
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Human CD27 Ligand (also CD70) is a 30kD type 2 transmembrane glycoprotein that is a member of the TNF superfamily. It contains a 20aa cytoplasmic region and a 155aa extracellular domain that shows multiple b-strands. It is an inducible trimer that occurs on B cells, T cells and NK cells. It regulates T cell dependent B cell differentiation into plasma cells and likely to promotes clonal expansion of T cells. Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. Applications: Suitable for use in ELISA, Western Blot and Flow Cytometry. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Flow Cytometry: 2.5ug labels 10e6 Raji cells from human Burkitt
Catalogue number: C2425-01B
Reactivities: Human
Hosts: Goat
Applications: ELISA, Flow Cytometry, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
P type: Pab
Isotype: IgG
Purity: Purified by antigen affinity chromatography.
Additional info: Recognizes human CD70 Ligand. Shows ~10% crossreactivity with recombinant mouse CD70 Ligand and recombinant human CD30 Ligand. Shows <1% crossreactivity with recombiniant human CD40 Ligand.

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