Home  >  Products  >  CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Surface Antigen CD70, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)
CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Surface Antigen CD70, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)

CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Surface Antigen CD70, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)

Cat no: C2425-02B

Supplier: United States Biological
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CD70 is not expressed on resting T and B lymphocytes but expression is induced on activation. Interaction of CD70 with its ligand CD27 is reported to play an important role in T-cell co-stimulation and the regulation of T-dependent B-cell activation and antibody production. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:25-1:50; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Hybridoma: P3U1 myeloma cells with spleen cells from F344/DuCrj rats. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2425-02B
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein G affinity chromatography.
Alternative names: CD27 L, CD70 Molecule
References: 1. Oshima, H. et al. (1998) Characterization of murine CD70 by molecular cloning and mAb. Int. Immunol.10:517
Additional info: Recognizes mouse CD70, a 30-33kD type II transmembrane protein belonging to the TNF superfamily.

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