Home  >  Products  >  CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Surface Antigen CD70, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7, Ki-24 antigen)
CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Surface Antigen CD70, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7, Ki-24 antigen)

CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Surface Antigen CD70, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7, Ki-24 antigen)

Cat no: C2425-02B4

Supplier: United States Biological
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CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. This antibody blocks CD70 binding to CD27. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)1ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2425-02B4
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Tesselaar K, et al. 1997. J. Immunol. 159:4959. 3. Akiba H, et al. 1999. J. Immunol. 162:7058.
Additional info: Recognizes mouse CD70.

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