Home  >  Products  >  CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)
CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)

CD70 (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)

Cat no: C2425-01LX

Supplier: United States Biological
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Human CD70 is not present on resting lymphocytes. CD70 is expressed after activation on about 20% of T cells and on about 70% of B cells. CD70 is a ligand for CD27 and it is also a member of the tumor necrosis factor gene family. Applications: Suitable for use in ELISA, Flow Cytometry, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2425-01LX
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 50mM sodium chloride. No preservative added.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
Alternative names: CD27 L, CD70 Molecule
References: 1. R.Q. Hintzen, et al, (1994) J Immunol 152: 1762-1773, 2. M.R. Bowman, et al, (1994) J Immunol 152: 1756-1761, 3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1137-1138, 4. K. Agematsu, et al, (1995) J Immunol 154: 3627-3635, 5. S Iwamoto, A Miyazaki, et al, (2005) J Leuk Biol 78: 383-392, 6. Wischhusen J, M Weller, et al. (2002) Cancer Res 62: 2592-2599, 7. P.J. Adams, A.L. Harris, et al.(2006) British J Cancer 95:298-306, 8. C Muller, R Kuppers, et al.(2010) Intl Immunol 22(4):289-298.
Additional info: Recognizes human CD70 at ~30kD. Inhibits T cell proliferation induced by dendritic cells.

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