Home  >  Products  >  CD71 (CD71 Antigen, p90, T9, Transferrin Receptor, TFR, TR, Transferrin Receptor Protein 1, TFR 1, TFR1, TFR-1, TFRC, TRFR)

CD71 (CD71 Antigen, p90, T9, Transferrin Receptor, TFR, TR, Transferrin Receptor Protein 1, TFR 1, TFR1, TFR-1, TFRC, TRFR)

Cat no: C2426-15F


Supplier: United States Biological
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CD71, a 95kD cell surface protein that is otherwise known as transferrin receptor. Recognizes native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the mouse. Applications: Suitable for use in Flow Cytometry, Functional Assays, and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:100-1:200; 10ul labels 10e6 cells Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Hybridoma: NSO myeloma cells with spleen cells from Lewis rats. Recommended Negative Control: I1904-82G1: IgG2a, Rat, Negative Control (Low Endotoxin) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2426-15F
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry, Immunohistochemistry
Size: 500ug
Form: Supplied as a liquid in PBS, pH 7.4. No preservatives added.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography. Endotoxin: <0.01EU/ug.
References: 1. Kissel, K. et al. (1998) Immunohistochemical localization of the murine transferrin receptor (TfR) on blood-tissue barriers using a novel anti-TfR monoclonal antibody. Histochem cell Biol. 110: 63-72. 2. Lee, H.J. et al. (2000) Targeting rat anti-mouse transferin receptor monoclonal antibodies through blood-brain barrier in mouse. J. Pharmacol Exp Ther. 292: 1048-52.
Additional info: Recognizes mouse CD71.

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