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CD71 (Transferrin Receptor, TR, Tfr, TfnrR) (FITC)

CD71 (Transferrin Receptor, TR, Tfr, TfnrR) (FITC)

Cat no: C2426-29B

Supplier: United States Biological
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Applications: Suitable for subset analysis of the developmental stage of mouse cells and as a proliferation marker. Applications in flow cytometry, immunoprecipitation and immunohistochemistry. Recommended Dilutions: Flow cytometry: use 1ug to stain 1x10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2426-29B
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 500ug
Form: Supplied as a liquid in 0.01M PBS, pH 7.4 containing 1% BSA, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G chromatography.
References: 1. Lesley, J., et al., (1982), Immunogenetics, 15:313. 2. Lesley, J., et al., (1984), Mol. Cell. Biol., 4(9): 1675. 3. Kemp, J.D., et al., (1987), J. Immunol., 138:2422. 4. Kemp, J.D., et al., (1989), Cell Immunol., 122:218.
Additional info: Recognizes the mouse transferrin receptor protein on the surface of most dividing cells. The function of the transferrin receptor is believed to be mainly nutritional. Alternatively, it has been suggested that a growth signal might be provided by the interaction of transferrin and transferrin receptor. The CD71 is present on most dividing cells, including normally cycling in vivo hematopoietic progenitor cells, mitogenically stimulated cells in vitro, some primary tumor cells and most proliferating cells in vitro.

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