CD79a Antibody

Cat no: 252272

Supplier: ABBIOTEC

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Description
Additional Information

The CD79a antigen (Immunoglobulin binding protein-1, IGBP-1) is an alpha/beta heterodimer cell membrane protein required in cooperation with CD79b for the initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor comple, Xenopus/Amphibian, (BCR). This cascade leads to BCR comple, Xenopus/Amphibian, internalization, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface e, Xenopus/Amphibian,pression and efficient differentiation of pro- and pre-B-cells. CD79a interacts with numerous kinases such as SYK, BLNK, Src-family tyrosine kinases. Defects in CD79a are a cause of non-Bruton type agammaglobulinemia, an immunodeficiency disease of the B-cell maturation pathway.

Catalogue number:	252272
Reactivities:	Human
Applications:	Immunofluorescence
Size:	0.1 mg
Accession:	P11912
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD79a.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody, FITC-conjugated Antibody
Isotype:	Rabbit Ig
Additional info:	CD79A; IGBP-1; Immunoglobulin binding protein-1; B-cell antigen receptor comple, Xenopus/Amphibian,-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Surface IgM-associated protein; Membrane-bound immunoglobulin-associated protein