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CD79a (B-cell Antigen Receptor Complex-associated Protein alpha Chain, Ig-alpha, MB-1 Membrane Glycoprotein, Membrane-bound Immunoglobulin-associated Protein, Surface IgM-associated Protein, IGA, MB1)

CD79a (B-cell Antigen Receptor Complex-associated Protein alpha Chain, Ig-alpha, MB-1 Membrane Glycoprotein, Membrane-bound Immunoglobulin-associated Protein, Surface IgM-associated Protein, IGA, MB1)

Cat no: C2431-10J

Supplier: United States Biological
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CD79a is a 47kD type I integral membrane protein, also known as mb-1 or Iga. It is a member of the Ig superfamily and disulphide-associated with CD79b (B29). The interaction of CD79a/CD79b heterodimer with B cell suface Ig forms B cell antigen complex. CD79a is expressed in B cells from early pre-B to plasma cell stage. It has been shown that CD79a is also weakly expressed in some precursors of T- and myeloid cells.CD79 mediates the transport of IgM to B cell surface and transduces signals initiated by BCR aggregation Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2431-10J
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Mason, DY., et al. 1991. J. Immunol. 147:2474. 2. Bhargava, P., et al. 2007. Am. J. Clin. Pathol. 128:306. 3. Zola, Heddy, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules: The CD markers. WILEY-LISS. 4. Astsaturov, IA., et al. 1996. Leukemia 10:769. 5. Mson, DY., et al. 1995 Blood. 86:1453. 6. Hashimoto, M., et al. 2002. J. Pathol. 197:341.
Additional info: Recognizes human CD79a.

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