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Products CD8 (CD 8, CD8 Antigen alpha Polypeptide, Leu2 T Lymphocyte Antigen, MAL, OKT8 T Cell Antigen, p32, T Cell Antigen Leu2, T Cell Surface Glycoprotein CD8 alpha Chain)
| Catalogue number: | C2259-12G1 |
| Reactivities: | Human, Non-Human Primate |
| Hosts: | Mouse |
| Applications: | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
| Size: | 100ug |
| Form: | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Purified by ion exchange chromatography |
| References: | 1. Zarkesh-Esfahani, H. et al. (2001) High-dose Leptin activates human leukocytes via receptor expression on monocytes. J. Immunol. 167: 4593 - 4599. 2. Manninen, A. et al. (2002) HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells. J. Exp.Med. 195 (8): 1023 -1032. 3. Parnes, J.R. (1989) Molecular biology and function of CD4 and CD8. Adv. Immunol. 44: 265-311. 4. Kap, Y.S. et al. (2009) A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. J Histochem Cytochem. 57: 1159-67. 5. Hovden, A.O. et al. (2011) Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses. BMC Immunol. 12: 2. 6. Nelson, M. et al. (2010) Characterization of lethal inhalational infection with Francisella tularensis in the common marmoset (Callithrix jacchus). J Med Microbiol. 59: 1107-13. 7. Gibbings, D.J. et al. (2007) CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses. BMC Immunol. 8: 12. 8. Junker, A. et al. (2007) Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain. 130: 2789-99. 9. Held, K. et al. (2011) Expression of HSV-1 encoded miRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates. J Virol. Jul 27. |
| Additional info: | Recognises the human CD8 cell surface glycoprotein expressed by a subset of peripheral blood T cells which express cytotoxic/suppressor activity. It is also expressed weakly on NK cells. Species Crossreactivity: Rhesus monkey |
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