Home  >  Products  >  CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, B7, B7.1, B7-1, BB1, CD28LG, CD28LG1, CTLA-4 Counter-receptor B7.1, LAB7)
CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, B7, B7.1, B7-1, BB1, CD28LG, CD28LG1, CTLA-4 Counter-receptor B7.1, LAB7)

CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, B7, B7.1, B7-1, BB1, CD28LG, CD28LG1, CTLA-4 Counter-receptor B7.1, LAB7)

Cat no: C2432-01A

Supplier: United States Biological
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Human CD80 (B7-1) is a costimulatory ligand for CD28 and CTLA-4. CD80 is expressed on activated B cells. Applications: Suitable for use in ELISA, Western Blot and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2432-01A
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.5. No preservative added.
P type: Mab
Isotype: IgM
Purity: Purified by size exclusion.
Alternative names: CD80 Molecule
References: 1. T. Yokochi, R.D. Holly & E.A. Clark, (1982) J Immunol 128: 823-827, 2. P.S. Linsley, et al, (1990) Proc Natl Acad Sci USA 87: 5031-5035, 3. N.K. Damle, et al, (1991) Eur J Immunol 21: 1277-1282, 4. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 682-684, 5. D. Mauri, et al, (1995) J Immunol 155: 118-127, 6. G.J. Freeman, et al, (1998) J Immunol 161:2708-2715.
Additional info: Recognizes human CD80 at ~60kD. Blocks adhesion to CD28/CTLA-4, blocks Th induced B cell Ig synthesis and blocks binding of soluble CD152 Ig fusion protein to CD80.

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