Home  >  Products  >  CD82 (C33 Antigen, IA4, Inducible Membrane Protein R2, KAI 1, KAI1, Kangai 1, Kangai1, Metastasis Suppressor Kangai 1, R2 leukocyte antigen, SAR2, ST6, Suppression of Tumorigenicity 6 Protein, Tetraspanin 27, Tspan-27, SAR2, ST6, TSPAN27)
CD82 (C33 Antigen, IA4, Inducible Membrane Protein R2, KAI 1, KAI1, Kangai 1, Kangai1, Metastasis Suppressor Kangai 1, R2 leukocyte antigen, SAR2, ST6, Suppression of Tumorigenicity 6 Protein, Tetraspanin 27, Tspan-27, SAR2, ST6, TSPAN27)

CD82 (C33 Antigen, IA4, Inducible Membrane Protein R2, KAI 1, KAI1, Kangai 1, Kangai1, Metastasis Suppressor Kangai 1, R2 leukocyte antigen, SAR2, ST6, Suppression of Tumorigenicity 6 Protein, Tetraspanin 27, Tspan-27, SAR2, ST6, TSPAN27)

Cat no: C2433-60D

Supplier: United States Biological
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CD82 (Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot:1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2433-60D
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, pH 7.4, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with sterile dH2O.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human CD82. Species Cross-Reactivity: mouse, rat.

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