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Products CD83 (B-cell activation protein, BL11, Cell Surface Protein HB15)
| Catalogue number: | C2435-08 |
| Reactivities: | Human |
| Hosts: | Rat |
| Applications: | Flow Cytometry, Western Blot |
| Size: | 50ug |
| Form: | Supplied as a liquid in PBS, 0.01% sodium azide. |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Purified by Protein G affinity chromatography. |
| References: | 1. The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells: M. Lechmann, et al.; J. Exp. Med. 194, 1813 (2001) 2. Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies: M. Lechmann, et al.; Protein Exp. Purif. 24, 445 (2002). |
| Additional info: | Recognizes human CD83. The binding affinity strongly increases after deglycosylation of mature DC. Does not inhibit DC mediated T-cell stimulation in mixed lymphocyte reactions. |
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