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CD83 (CD83 Antigen, hCD83, B-cell Activation Protein, Cell Surface Protein HB15)

CD83 (CD83 Antigen, hCD83, B-cell Activation Protein, Cell Surface Protein HB15)

Cat no: C2435-04K

Supplier: United States Biological
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CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2435-04K
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Knapp, W., et al. 1989. Leucocyte Typing IV. Oxford University Press, New York. 2. Zhou, L., et al. 1995. J. Immunol. 154:3821. 3. Cao, W., et al. 2005. Biochem. J. 385:85. 4. Lore, K., et al. 2002. AIDS 16:683. 5. Cho, H., et al. 2007. Physiol Genomics doi:10.1152/physiolgenomics.00051.2006. 6. Kozlow, E., et al. 1993. Blood 81:454. 7. Zhou, L., et al. 1992. J. Immunol. 149:735. 8. Zhou, L., et al. 1995. Blood 86:3295.
Additional info: Recognizes human CD83. Species Crossreactivity: chimpanzee, baboon, cynomolgus, rhesus.

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