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CD84 (SLAM Family Member 5, Cell Surface Antigen MAX.3, Hly9-beta, Leukocyte Differentiation Antigen CD84, Signaling Lymphocytic Activation Molecule 5, SLAMF5)

CD84 (SLAM Family Member 5, Cell Surface Antigen MAX.3, Hly9-beta, Leukocyte Differentiation Antigen CD84, Signaling Lymphocytic Activation Molecule 5, SLAMF5)

Cat no: C2436-12J

Supplier: United States Biological
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CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of (preferentially on CD45RO+) T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. The antibody CD84.1.21 is able to enhance CD3 induced IFN-g production and partially block CD84-Ig binding to lymphocytes. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2436-12J
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Martin, M., et al. 2001. J. Immunol. 167:3668. 2. SayOs, J., et al. 2001. Blood 97:3867. 3. Morra, M., et al. 2001. EMBO 20:5840. 4. Morra, M., 2001. J. Biol. Chem. 276:36809. 5. Romero, X., et al. 2004. Tissue Antigens 64:132. 6. de la Fuente, MA., et al. 1997. Blood 90(6):2398. 7. Tangye, SG., et al. 2002. Eur. J. Immunol. 32(6):1640. 8. Tangye, SG., et al. 2003. J. Immunol. 171:2485. 9. Martin, M., et al. 2001. J. Immunol. 167:3668.
Additional info: Recognizes human CD84.

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