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CD88 (CD88 Antigen, Anaphylatoxin Receptor, C5a Anaphylatoxin Chemotactic Receptor, C5aR, C5a-R, C5a Ligand, C5R1)

CD88 (CD88 Antigen, Anaphylatoxin Receptor, C5a Anaphylatoxin Chemotactic Receptor, C5aR, C5a-R, C5a Ligand, C5R1)

Cat no: C2439-61C1

Supplier: United States Biological
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Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:200; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2439-61C1
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 500ug
Form: Supplied as a liquid in PBS, pH 7.4. No preservatives added.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein G affinity chromatography.
Alternative names: Complement Component 5 Receptor 1, Complement Component 5 Receptor 2
References: 1. Soruri, A. et.al. (2003) Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody. Immunol. Lett. 88:47-52, 2. Godau, J. et.al. (2004) C5a initiates the inflammatory cascade in immune complex peritonitis. J. Immunol.173:3437-3445, 3. Baelder, R. et.al. (2005) Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppress airway hyperresponsiveness and airway inflammation. J. Immunol.174:783-789.
Additional info: Recognizes mouse CD88, a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR.

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