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CD88 (CD88 Antigen, Anaphylatoxin Receptor, C5a Anaphylatoxin Chemotactic Receptor, C5aR, C5a-R, C5a Ligand, C5R1)

Cat no: C2439-61E


Supplier: United States Biological
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Applications: Suitable for use in Flow Cytometry, Immunohistochemistry (frozen and paraffin), and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Hybridoma: X63-Ag8 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2439-61E
Reactivities: Human, Non-Human Primate
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Size: 200ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography.
Alternative names: Complement Component 5 Receptor 1, Complement Component 5 Receptor 2
References: 1. Opperman, M. et al. (1993) Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain J. Immunol. 151: 3785 - 3794, 2. Opperman, M. et al. (1995) Antibodies from the myeloid panel that react with the C5a receptor and anatagonize C5a biological activity. In: Schlossman, S.F. (ed.) Leucocyte Typing V. O.U.P: 955-956, 3. Werfel, T. et al. (1995) Binding of anti-C5a receptor (C5aR) antibodies to cells of clinically normal human skin. In: Schlossman, S.F. (ed.) Leucocyte Typing V. O.U.P.: 957-959, 4. Oppermann, M. (1995) Cluster report: (C5a receptor). In: Schlossman, S.F. (ed.) Leucocyte Typing V. O.U.P. 953-954, 5. Oppermann, M. and G
Additional info: Recognizes human the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Species Crossreactivity: Monkey.

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