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CD90 (Thy-1 Membrane Glycoprotein, CDw90, Thy-1 Antigen, THY1)

CD90 (Thy-1 Membrane Glycoprotein, CDw90, Thy-1 Antigen, THY1)

Cat no: C2441-51H

Supplier: United States Biological
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CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+ cells, a subset of fetal liver cells and fetal thymocytes, fibroblast, activated endothelial cells, and some leukemia cell lines. CD34+CD90+ cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with beta2 and beta3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, inhibits hematopoietic stem cells proliferation and differentiation. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.5ug/10e5 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2441-51H
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by affinity chromatography.
References: 1. Craig, W., et al. 1993. J. Exp. Med. 177:1331. 2. McKenzie, J.L., et al. 1981. J. Immunol. 126:843. 3. Avalos, A.M., et al. 2002. Biol.Res. 35:231. 4. Wetzel, A., et al. 2004. J. Immunol. 172:3850.
Additional info: Recognizes human CD90. Species Crossreactivity: baboon, cynomolgus, rhesus, pigtailed macaque

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