Home  >  Products  >  CD92 (CD92 Antigen, CD92 Protein, CDw92, CDw92 Antigen, Choline Transporter-like Protein 1, CHTL1, CTL1, RP11-287A8.1, Solute Carrier Family 44 Member 1, SLC44A1), Low Endotoxin
CD92 (CD92 Antigen, CD92 Protein, CDw92, CDw92 Antigen, Choline Transporter-like Protein 1, CHTL1, CTL1, RP11-287A8.1, Solute Carrier Family 44 Member 1, SLC44A1), Low Endotoxin

CD92 (CD92 Antigen, CD92 Protein, CDw92, CDw92 Antigen, Choline Transporter-like Protein 1, CHTL1, CTL1, RP11-287A8.1, Solute Carrier Family 44 Member 1, SLC44A1), Low Endotoxin

Cat no: C2441-98A1

Supplier: United States Biological
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CDw92 (isoform 3), also known as CTL1, is a 70kD multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine. Reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10. Applications: Suitable for use in Flow Cytometry, Functional Assays, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul Immunohistochemistry: frozen sections Optimal dilutions to be determined by the researcher. Positive Control: Human tonsil Hybridoma: X63Ag.653 myeloma cells with spleen cells from Balb/c mice. Recommended Secondary Antibodies: I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo I1904-06H IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo I1904-14C: IgG, Fc (HRP) Pab Gt xMo Recommended Negative Control: I1904-84Q3: IgG2b Murine Negative Control Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2441-98A1
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 500ug
Form: Supplied as a liquid in PBS, pH 7.4. No preservatives added. Endotoxin: < 0.01EU/ug
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein G affinity chromatography
References: 1. Wille, S. et al. (2001) Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically in dendritic cells. J. Immunol. 167: 5795-5804, 2. O
Additional info: Recognizes human CD92. Specific for the C

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