Home  >  Products  >  CD94 (CD94 Antigen, Killer Cell Lectin-like Receptor Subfamily D Member 1, KLRD1, KLRD1 Protein, KP43, Natural Killer Cells Antigen CD94, NK Cell Receptor) (FITC)
CD94 (CD94 Antigen, Killer Cell Lectin-like Receptor Subfamily D Member 1, KLRD1, KLRD1 Protein, KP43, Natural Killer Cells Antigen CD94, NK Cell Receptor) (FITC)

CD94 (CD94 Antigen, Killer Cell Lectin-like Receptor Subfamily D Member 1, KLRD1, KLRD1 Protein, KP43, Natural Killer Cells Antigen CD94, NK Cell Receptor) (FITC)

Cat no: C2442-09A1

Supplier: United States Biological
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CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes. CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: Neat-1:10. 10ul labels 10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Recommeded Negative Control: I1904-78R3: IgG1 Murine Negative Control (FITC) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Catalogue number: C2442-09A1
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
References: 1. Phillips, J. et al. (1996) CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B and HLA-C allotypes. Immunity. 5: 163 - 172, 2. Braud, V. et al. (1998) HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature. 391: 795 - 799, 3. Tomasec, P. et al. (2000) Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science. 287: 1031 - 1033, 4. S
Additional info: Recognizes human CD94. Reported to inhibit the binding of CD94 to HLA-E and HLA-G.

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