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Cdc13 (c myc gene single strand binding protein 2, G2/mitotic specific cyclin, RNA binding motif single stranded interacting protein 1 antibody, single stranded DNA binding protein MSSP1, SRC2, suppressor of cdc13 with RNA binding motif 2, YC1)

Cdc13 (c myc gene single strand binding protein 2, G2/mitotic specific cyclin, RNA binding motif single stranded interacting protein 1 antibody, single stranded DNA binding protein MSSP1, SRC2, suppressor of cdc13 with RNA binding motif 2, YC1)

Cat no: C2550-10A

Supplier: United States Biological
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RBMS1 gene product is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Multiple transcript variants of RBMS1 resulting from alternative splicing and encoding different isoforms, have been described. Several of these were isolated by virtue of their binding to either strand of an upstream element of c-myc (MSSPs), or by phenotypic complementation of cdc2 and cdc13 mutants of yeast (scr2), or as a potential human repressor of HIV-1 and ILR-2 alpha promoter transcription (YC1). Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2550-10A
Reactivities: Yeast/Fungi
Hosts: Mouse
Applications: Immunoprecipitation, Western Blot
Size: 200ug
Form: PBS
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein A affinity chromatography.
Alternative names: c myc gene single strand binding protein 2, G2/mitotic specific cyclin, RNA binding motif single stranded interacting protein 1 antibody, single stranded DNA binding protein MSSP1, SRC2, suppressor of cdc13 with RNA binding motif 2, YC1
References: This product has been used in:Decottignies A et al. In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis. J Cell Sci 114:2627-40 (2001).
Additional info: Species Crossreactivity: Crossreacts with S. pombe.

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