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CDCP1 (Cub Domain Containing Protein1, SIMA135)

Cat no: C2566-01A


Supplier: United States Biological
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The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2566-01A
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: CD318, CD318 antigen, CUB Domain Containing Protein 1, FLJ13772, FLJ22375, FLJ22969, Membrane glycoprotein gp140, MGC31813, Subtractive immunization M plus HEp3 associated 135kD protein, Transmembrane and associated with src kinases, TRASK
References: Scherl-Mostageer M et al. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Oncogene 20:4402-8 (2001).
Additional info: Species Crossreactivity: Crossreacts with Human.

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