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CDDO Methyl Ester

CDDO Methyl Ester

Cat no: 005841

Supplier: United States Biological
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CDDO Methyl Ester is a synthetic triterpenoid that inhibits IkBa kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer. Form: White to Off-White Solid Melting Point: 215-219 degrees C Solubility: Chloroform, Methanol (Sparingly)
Catalogue number: 005841
Size: 5mg
Form: White to Off-White Solid
Alternative names: 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Methyl Ester; Bardoxolone Methyl; CDDO-Me; Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; NSC 713200; RTA 402;
References: Shishodia, S. et al.: Clin. Cancer Res., 12, 1828 (2006); Konopleva, M. et al.: Leukemia, 19, 1350 (2005); Deeb, D. et al.: Cancers, 2, 1779 (2010); Gao, X. et al.: J. Exp. Therap. Oncol., 9, 119 (2011);

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