CDK2, CT (Cyclin-dependent Kinase 2, Dr.75152)

Cat no: C2572-41

Supplier: United States Biological

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Regulated progression through the cell cycle requires sequential expression of a family of proteins called cyclins. Upon their induction, cyclins form complexes with specific cyclin-dependent kinases (CDKs), creating active holoenzymes that phosphorylate target proteins required for cell-cycle progression. One study demonstrates that inhibition of cdc25a and cdk1, but not cdk2 is essential for cell cycle lengthening in zebrafish. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Control Peptide: C2572-41D Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C2572-41
Reactivities:	Zebrafish/Fish
Hosts:	Rabbit
Applications:	ELISA, Western Blot
Size:	250ul
Form:	Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
References:	1. Brown, NR et al (2007) Cell Cycle 6:1350-1359. 2. Dalle Nogare, DE et al (2009) Dev. Biol. 326(1):131-142.
Additional info:	Recognizes zebrafish CDK-2.

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CDK2, CT (Cyclin-dependent Kinase 2, Dr.75152)

Cat no: C2572-41

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