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cdk2 (Cyclin-dependent Kinase 2)

cdk2 (Cyclin-dependent Kinase 2)

Cat no: C2572-05H

Supplier: United States Biological
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Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2572-05H
Reactivities: Xenopus/Amphibian
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added.
P type: Mab
Isotype: IgG2a
Purity: Purified
Alternative names: Cdc2 related protein kinase, Cdk 2, CDK2, Cell division kinase 2, Cell division protein kinase 2, p33 protein kinase, p33(CDK2)
Additional info: Recognizes xenopus Cyclin-dependent Kinase 2 at ~34kD.

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