Cyclin-dependent kinase 4 (CDK4) belongs to the Ser/Thr protein kinase family. CDK4 is a subunit of the protein kinase complex that is important for cell cycle G1 phase progression. Mutations in CDK4 have been implicated in tumor formation. Multiple alternatively spliced variants and polyadenylation sites have been reported for this gene.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Western Blot: 0.5-1.0ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.