Home  >  Products  >  cdk5, CT (Cyclin-Dependent Kinase 5, Cdk 5, Cell Division Protein Kinase 5, p31, Protein Kinase CDK5 Splicing, PSSALRE, Serine/threonine-protein Kinase PSSALRE, Tau Protein Kinase II Catalytic Subunit, TPKII Catalytic Subunit)

cdk5, CT (Cyclin-Dependent Kinase 5, Cdk 5, Cell Division Protein Kinase 5, p31, Protein Kinase CDK5 Splicing, PSSALRE, Serine/threonine-protein Kinase PSSALRE, Tau Protein Kinase II Catalytic Subunit, TPKII Catalytic Subunit)

Cat no: C2575-01B


Supplier: United States Biological
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Cdk5 is ubiquitously expressed, but expression and activity is highest in post mitotic neurones, where p35 and p39 are highly expressed. Deregulation of this kinase is neurotoxic and might contribute to the pathogenesis of Alzheimer
Catalogue number: C2575-01B
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Immunoprecipitation, Western Blot
Size: 50ul
Form: Supplied as a liquid, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Serum
Alternative names: Cyclin Dependent Kinase 5, Crk6
References: 1. Cheung, Z.H. et al. (2006) Synaptic roles of Cdk5: Implications in higher cognitive functions and neurodegenerative diseases. Neuron. 50: 13-18. 2. Pareek, T.K. and Kulkarni, A.B. (2006) Cdk5: a new player in pain signaling. Cell Cycle. 5: 585-588. 3. Cruz, J.C. and Tsai, L. (2004) Cdk5 deregulation in the pathogenesis of Alzheimer's disease. Trends in Mol. Med. 10: 452-458.
Additional info: Recognizes human Cdk5. Species Crossreactivity: mouse and rat.

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