Cdk7 Antibody

Cat no: 251729

Supplier: ABBIOTEC

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Description
Additional Information

Cyclin-dependent kinase 7 (Cdk7) is the catalytic subunit of the CDK-activating kinase (CAK) comple, Xenopus/Amphibian,, a serine-threonine kinase. Cdk7 activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. Cdk7 comple, Xenopus/Amphibian,ed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts.

Catalogue number:	251729
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P50613
Antigen:	Recombinant human Cdk7.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2b
Additional info:	Cdk7; Cell division protein kinase 7; CDK-activating kinase; CAK; CAK1; TFIIH basal transcription factor comple, Xenopus/Amphibian, kinase subunit; 39 kDa protein kinase; p39 Mo15; STK1; CDK7; MO15