Home  >  Products  >  CDK7, NT (Novel Protein (Zgc:85821), CH211-198E13.4, Dr.3533, CH211-198E13.4-001, zgc:85821)
CDK7, NT (Novel Protein (Zgc:85821), CH211-198E13.4, Dr.3533, CH211-198E13.4-001, zgc:85821)

CDK7, NT (Novel Protein (Zgc:85821), CH211-198E13.4, Dr.3533, CH211-198E13.4-001, zgc:85821)

Cat no: C2577-09A

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Regulated progression through the cell cycle requires sequential expression of a family of proteins called cyclins. Upon their induction, cyclins form complexes with specific cyclin-dependent kinases (CDKs), creating active holoenzymes that phosphorylate target proteins required for cell-cycle progression. CDK7, the catalytic subunit of the CDK- activating kinase (CAK) complexes with Cyclin H. Within humans, the CAK is involved in the regulation of RNA polymerase II when complexed with the core-TFIIH basal transcription factor, allowing for elongation of transcripts. However, the function of the CDK7 ortholog in zebrafish has not yet been isolated. Sequence analysis has shown that zebrafish CDK7 cDNAs encode proteins with 86% identity to human orthologs. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Optimal dilutions to be determined by the researcher. Control Peptide: C2577-09E Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2577-09A
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.1% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Liu, QY (2007) Cell Res. 17(2): 163-173. 2. Tirode, F et al (1999) Mol. Cell 3: 87-95. 3. Tsang, WY et al (2007) J. Cell Biol. 178: 621-633.
Additional info: Recognizes zebrafish CDK7.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave