CDKN1B (3D8) Antibody

Cat no: 253004

Supplier: ABBIOTEC

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Description
Additional Information

p27 (Cyclin-dependent kinase inhibitor p27) is a regulator of cell cycle progression. p27 is involved in G1 arrest. P27 is a potent inhibitor of cyclin E- and cyclin A-CDK2 comple, Xenopus/Amphibian,es. P27 forms a comple, Xenopus/Amphibian, with cyclin type D-CDK4 comple, Xenopus/Amphibian,es and is involved in the assembly, stability, and modulation of CCND1-CDK4 comple, Xenopus/Amphibian, activation. P27 acts either as an inhibitor or an activator of cyclin type D-CDK4 comple, Xenopus/Amphibian,es depending on its phosphorylation state and/or stoichometry. Defects in CDKN1B are the cause of multiple endocrine neoplasia type 4 (MEN4). Multiple endocrine neoplasia (MEN) syndromes are inherited cancer syndromes of the thyroid. MEN4 is a MEN-like syndrome with a phenotypic overlap of both MEN1 and MEN2.

Catalogue number:	253004
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P46527
Antigen:	Purified recombinant fragment of human CDKN1B e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3D8
Additional info:	p27; Kip1; p27/kip1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1; CDKN1B; KIP1