Home  >  Products  >  CDT1 (CDT, CDT-1, Chromatin Licensing and DNA Replication Factor 1, DUP, hDUP, human homolog of Drosophila Double Parked, RIS2)
CDT1 (CDT, CDT-1, Chromatin Licensing and DNA Replication Factor 1, DUP, hDUP, human homolog of Drosophila Double Parked, RIS2)

CDT1 (CDT, CDT-1, Chromatin Licensing and DNA Replication Factor 1, DUP, hDUP, human homolog of Drosophila Double Parked, RIS2)

Cat no: C2300-01B

Supplier: United States Biological
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Cdt1, a DNA replication factor involved in the formation of the DNA pre-replication complex, in conjunction with CDC6 (cell division control protein 6 homolog). Cdt1 has been implicated as a potential oncogene, with its over-expression resulting in the activation of DNA damage checkpoints and abnormal replication. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:64,000 Western Blot: 1-3ug/ml detects ~60kD band observed in Human Ovary lysates (calculated MW of 60.4kD according to NP_112190.2). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2300-01B
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: DNA replication factor, Double parked, Drosophila, homolog of, Double parked, RIS2, chromatin licensing and DNA replication factor 1, DUP, CDT1
References: 1. Whittaker AJ, Royzman I, Orr-Weaver TL. Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts. Genes Dev. 2000 Jul 15;14(14):1765-76
Additional info: Recognizes human CDT1.

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