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CEACAM1, CEACAM5, CEACAM6 (CD66a,c,e)

Cat no: C2589-53E

CEACAM1, CEACAM5, CEACAM6 (CD66a,c,e)

CD66a/c/e are members of the CEA (carcinoembryonic antigen) family of the Ig superfamily. CD66 plays a role in hemophilic and heterophilic adhesion. CD66a, also known as CEACAM1 and BGP (biliary glycoprotein), is mainly expressed on granulocytes, binds to CD66a, c, e, and CD62E. CD66c (known as CEACAM6, NCA) is expressed on granulocytes and epithelial cells. The ligands of CD66c are CD66a-e, CD62E and Galectins. CD66e molecule is also called as CEA or CEACAM5, primarily found on epithelial cells. CD66e binds to CD66a, c and e.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: (same/less than)0.125ug/10e5 cells in 100ul\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C2589-53E

Size

100ug

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG2b,k

References

1. Zola, H., et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers. Wiley-Liss. A John Wiley & Sons, Inc. Publication

Additional Info

Recognizes an antigen epitope shared by human CD66a, c and e.

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