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CEBP gamma (CCAAT/enhancer Binding Protein (C/EBP), gamma, C/EBP gamma, CCAAT/enhancer-binding Protein gamma, GPE1BP, IG/EBP-1)

CEBP gamma (CCAAT/enhancer Binding Protein (C/EBP), gamma, C/EBP gamma, CCAAT/enhancer-binding Protein gamma, GPE1BP, IG/EBP-1)

Cat no: C2589-93B

Supplier: United States Biological
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CCAAT/enhancer binding protein (C/EBP) gamma is a family of transcription factors all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta, gamma, delta, that form homodimers and/or form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBP gamma may cooperate with Fos to bind PRE-enhancer elements. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA:1:2000 Western Blot:1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Lung and A549 cell lysates Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 monthsat -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Peptide Blocking: Corresponding peptide is available for Peptide Blocking studies. See C2589-93B-P. Antibody
Catalogue number: C2589-93B
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Mullins DN, Crawford EL, Khuder SA, Hernandez DA, Yoon Y, Willey JC. CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma. BMC Cancer. 2005 Oct 29;5:141. PMID: 16255782
Additional info: Recognizes human CEBPG at ~26kD. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 16.4kD.

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