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Cebpb (CCAAT/Enhancer-binding Protein beta, C/EBP beta, AGP/EBP, Interleukin-6-dependent-binding Protein, IL-6DBP, Liver-enriched Transcriptional Activator, LAP)

Cebpb (CCAAT/Enhancer-binding Protein beta, C/EBP beta, AGP/EBP, Interleukin-6-dependent-binding Protein, IL-6DBP, Liver-enriched Transcriptional Activator, LAP)

Cat no: C2589-89D

Supplier: United States Biological
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C/EBP beta (also known as CCAAT/enhancer-binding protein beta, interleukin 6-dependent DNA-binding protein, and nuclear factor of interleukin 6 [NF-IL6]) is a member of the basic leucine zipper C/EBP transcription factor family. C/EBP has three isoforms that include C/EBPb, LAP, and LIP (35kD, 32kD, and 20kD, respectively). This protein is localized in the nucleus and functions as a transcription factor in immune, inflammatory, acute-phase, cytokine, collagen type I gene expression. It is upregulated by growth hormones and has been shown to interact with CEBP-a, CEBP-d, CEBP-g, CEBP-e, and CEBP-z. The C/EBP beta protein can be modified by phosphorylation and ubiquitination. Applications: Suitable for use in Immunoprecipitation, Immunofluorescence and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2589-89D
Reactivities: Mouse, Rat
Hosts: Mouse
Applications: Immunofluorescence, Immunoprecipitation, Western Blot
Size: 25ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by Protein G affinity chromatography.
References: 1. Chang C, et al. 1990. Mol. Cell Biol. 10:6642. 2. Eaton E, et al. 2001. J. Cell Physiol. 189:91. 3. Piwien-Pilipuk G, et al. 2002. J. Biol. Chem. 277:44557. 4. Hattori T, et al. 2003. Oncogene. 22:1273.
Additional info: Recognizes LIP. Species Crossreactivity: mouse and rat. Does not react with human LIP.

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