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Cecropin B (CECB1, CECB2, Lepidopteran A/B)

Cat no: C2592-01A


Supplier: United States Biological
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Cecropins are produced by insects, particularly under conditions of infection. Cecropins are bioactive peptides that exhibit activities by interacting with membranes and forming transmembrane channels that allow the free flow of electrolytes, metabolites and water across the phospholipid bilayers. Cecropins A, B and D are close homologues consisting of 35-39 residues. They are found in the pupae of the cecropin moth, but related homologues named lepodopteran, bactericidin, moricin and sarcotoxin are produced by other insects. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2592-01A
Hosts: Rabbit
Applications: ELISA, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A affinity chromatography.
Alternative names: CECB1, CECB2, Lepidopteran A/B
References: Bechinger B Structure and functions of channel-forming peptides: magainins, cecropins, melittin and alamethicin. J Membr Biol 156:197-211 (1997). PubMed: 9096062. Kato Y et al. Expression and characterization of cDNAs for cecropin B, an antibacterial protein of the silkworm, Bombyx mori. Insect Biochem Mol Biol 23:285-90 (1993). PubMed: 8485525 Brey PT et al. Role of the integument in insect immunity: epicuticular abrasion and induction of cecropin synthesis in cuticular epithelial cells. Proc Natl Acad Sci U S A 90:6275-9 (1993). PubMed: 8327509. Taniai K et al. Isolation and nucleotide sequence of cecropin B cDNA clones from the silkworm, Bombyx mori. Biochim Biophys Acta 1132:203-6 (1992). PubMed: 1390892. Gudmundsson GH et al. The cecropin locus. Cloning and expression of a gene cluster encoding three antibacterial peptides in Hyalophora cecropia. J Biol Chem 266:11510-7 (1991). PubMed: 1711035 Search PubMed (MEDLINE) for references to Cecropin B
Additional info: Recognizes cecropin B. The antibody may also recognize naturally occurring cecropin A. Species Crossreactivity: Reacts with Silk worm.

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