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CFTR (Cystic Fibrosis Transmembrane Conductance Regulator, ATP-binding Cassette Sub-family C Member 7, Channel Conductance-controlling ATPase, cAMP-dependent Chloride Channel, ABCC7)

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator, ATP-binding Cassette Sub-family C Member 7, Channel Conductance-controlling ATPase, cAMP-dependent Chloride Channel, ABCC7)

Cat no: C9040-01C

Supplier: United States Biological
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This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 2.5-5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C9040-01C
Reactivities: Human
Hosts: Goat
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human CFTR.

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