CGB (D131) Peptide

Choriogonadotropin is a hormone produced by the placenta in the first trimester of pregnancy and exists as a heterodimer formed from a unique beta chain and an alpha chain common to all gonadotropins. The unique beta chain confers biological specificity to choriogonadotropin, luteinizing hormone and follicle stimulating hormone. The secreted alpha subunit maps to human chromosome 6 and the beta subunit of choriogonadotropin maps to human chromosome 19. Choriogonadotropin stimulates the ovaries to produce and maintain normal levels of the steroids essential for maintaining pregnancy, including estrogen and progesterone. Choriogonadotropin is a member of the cystine knot growth-factor superfamily, a group of proteins that contain a distinct arrangement of six cysteine residues and are expressed in placenta. The proper secretion and dimerization of choriogonadotropin depends on the conformation of the cystine knot, although biological activity is independent of this conformation.

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SPECIFICATIONS

Catalog Number

BS1159P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide CGB (D131). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P01233

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1159 CGB (D131) pAb.

Alternative Names

CG beta; CG-beta; CGB 3; CGB 5; CGB 7; CGB; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin subunit beta; Chorionic gonadotrophin chain beta; Chorionic gonadotropin beta 3 subunit; Chorionic gonadotropin beta 3 subunit precursor; Chorionic gonadotropin beta chain; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta subunit; hCGB; Choriogonadotropin beta; hCG beta