Home  >  Products  >  Chak, CT (TRPM7, Transient Receptor Potential Cation Channel Subfamily M Member 7, Channel-kinase 1, Long Transient Receptor Potential Channel 7, LTrpC-7, LTrpC7, Transient Receptor Potential-phospholipase C-interacting Kinase, TRP-PLIK)
Chak, CT (TRPM7, Transient Receptor Potential Cation Channel Subfamily M Member 7, Channel-kinase 1, Long Transient Receptor Potential Channel 7, LTrpC-7, LTrpC7, Transient Receptor Potential-phospholipase C-interacting Kinase, TRP-PLIK)

Chak, CT (TRPM7, Transient Receptor Potential Cation Channel Subfamily M Member 7, Channel-kinase 1, Long Transient Receptor Potential Channel 7, LTrpC-7, LTrpC7, Transient Receptor Potential-phospholipase C-interacting Kinase, TRP-PLIK)

Cat no: C3445-26F

Supplier: United States Biological
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Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1-10ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Immunocytochemistry: 0.1-1ug/ml Immunoprecipitation: 1-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C3445-26F
Reactivities: Mouse
Hosts: Mouse
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH7.4, 0.09% sodium azide, 50% glycerol.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes mouse TRPM7 at ~220kD. Species sequence homology: Human, rat.

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