Quick Search
Products Chelerythrine chloride (NSC 36405, 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride)
![Chelerythrine chloride (NSC 36405, 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride)](/system/suppliers/default_product_images/000/000/160/main/US-Biological-Life-Sciences.jpg?1386100414)
| Catalogue number: | 044663 |
| Size: | 1mg |
| Purity: | >98% (NMR) |
| Alternative names: | NSC 36405, 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride |
| References: | Product Reference: ? Chelerythrine is a potent and specific inhibitor of protein kinase C: J.M. Herbert, et al.; BBRC 172, 993 (1990)?Antiplatelet effects of chelerythrine chloride isolated from Zanthoxylum simulans: F.N. Ko, et al.; Biochim. Biophys. Acta 1052, 360 (1990)?Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C: W.D. Jarvis, et al.; Cancer Res. 54, 1707 (1994)?Role of c-jun in human myeloid leukemia cell apoptosis induced by pharmacological inhibitors of protein kinase C: A.J. Freemerman, et al.; Mol. Pharmacol. 49, 788 (1996)?Angoline and chelerythrine, benzophenanthridine alkaloids that do not inhibit protein kinase C: S.K. Lee, et al.; J. Biol. Chem. 273, 19829 (1998)?Inhibition of protein kinase C translocation from cytosol to membrane by chelerythrine: M.D. Chao, et al.; Planta Med. 64, 662 (1998)?Axonal transport is inhibited by a protein kinase C inhibitor in cultured isolated mouse dorsal root ganglion cells: H. Hiruma, et al.; Brain. Res. 826, 135 (1999)?Activation of p38 and c-Jun N-terminal kinase pathways and induction of apoptosis by chelerythrine do not require inhibition of protein kinase C: R. Yu, et al.; J. Biol. Chem. 275, 9612 (2000)?In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo: S.J. Chmura, et al.; Clin. Cancer Res. 6, 737 (2000)?Identification of chelerythrine as an inhibitor of BclXL function: S.L. Chan, et al.; J. Biol. Chem. 278, 20453 (2003)?Chelerythrine and other benzophenanthridine alkaloids block the human P2X7 receptor: A.N. Shemon, et al.; Br. J. Pharmacol. 142, 1015 (2004)?The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine: J. Malikova, et al.; Cell Biol. Toxicol. 22, 439 (2006)?Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism: K.F. Wan, et al.; J. Biol. Chem. 283, 8423 (2008)?Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells: J. Vrba, et al.; Toxicol. In Vitro. 22, 1008 (2008)?Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice: X.F. Niu, et al.; Fitoterapia 82, 620 (2011) ? |
Get the Best Promotions
