Chemerin Peptide

Cat no: BS60386P

Supplier: Bioworld Technology, Inc.

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Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.

Catalogue number:	BS60386P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q99969
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Chemerin. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Retinoic acid receptor responder protein 2; RAR-responsive protein TIG2; Tazarotene-induced gene 2 protein; RARRES2; TIG2
Additional info:	This peptide can be used with studies using BS60386 Chemerin pAb.

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Chemerin Peptide

Cat no: BS60386P

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