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Chemerin, Recombinant, Human (Retinoic Acid Receptor Responder Protein 2, RAR-responsive Protein TIG2, Tazarotene-induced Gene 2 Protein, RARRES2, TIG2)

Cat no: C3890-02

Chemerin, Recombinant, Human (Retinoic Acid Receptor Responder Protein 2, RAR-responsive Protein TIG2, Tazarotene-induced Gene 2 Protein, RARRES2, TIG2)

Chemerin is a chemoattractant expressed in white adipose, liver and lung tissues. Chemerin is a ligand for the G-protein coupled receptor known as ChemR23 (or chemokine-like receptor-1), which is expressed mainly on dendritic cells, macrophages and some adipocytes. Recombinant human Chemerin, produced in E. coli, is a non-glycosylated protein containing 138aa and having a total molecular mass of 16kD.\n\nSource: \nRecombinant corresponding to human Chemerin, expressed in E. coli.\n\nAA Sequence:\nMELTEAQRRG LQVALEEFHK HPPVQWAFQE TSVESAAVDTP FPAGIFVRLE FKLQQTSRK RDWKKPECKV RPNGRKRKCL ACIKLGSEDK VLGRLVHCPI ETQVLREAEE HQETQCLRVQ RAGEDPHSFY FPGQFAFS\n\nMolecular Weight: \n~16kD\n\nEndotoxin Level:\n<0.01ng/ug\n\nBiological Activity:\nRecombinant human Chemerin has full biological activity when compared standards. The ED50, as determined by its ability to chemoattract human Chem23R transfected BaF3 mouse pro-B cells, is typically 4-20ng/ml.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

C3890-02

Size

25ug

Form

Supplied as a lyophilized powder from 0.2% TFA. Reconstitute with sterile dH2O to 0.1mg/ml, which can be further diluted into other aqueous solutions.

Purity

~98% (SDS-PAGE, HPLC)

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