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CHI3L1 (chitinase 3-like 1 (cartilage glycoprotein-39), 39kD synovial protein, ASRT7, Cartilage Glycoprotein 39, CGP-39, Chitinase-3-like Protein 1, DKFZp686N19119, FLJ38139, GP39, GP-39, hCGP-39, HC-gp39, HCGP-3P, YKL40, YKL-40, YYL-40)

Cat no: C3980

CHI3L1 (chitinase 3-like 1 (cartilage glycoprotein-39), 39kD synovial protein, ASRT7, Cartilage Glycoprotein 39, CGP-39, Chitinase-3-like Protein 1, DKFZp686N19119, FLJ38139, GP39, GP-39, hCGP-39, HC-gp39, HCGP-3P, YKL40, YKL-40, YYL-40)

Chitinase 3-Like-1 (CHI3L1) is a recently discovered human glycoprotein which is related in amino acid sequence to the chitinase protein family, but has no chitinase activity. CHI3L1 is upregulated in a number of cancers and in non-neoplatic disease states characterized by chronic inflammation and tissue remodeling. Its pattern of expression is associated with pathogenic processes related to inflammation, extracellular tissue remodeling, fibrosis and solid carcinomas. CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:250-1:500\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nMouse F0 myeloma cells with spleen cells from Balb/c mice.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C3980

Size

50ul

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH7.4, 0.1% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2b,k

References

1. Kazakova MH, et al., (2009) Folia Med. 51(1):5-14 2. Bonneh-Barkay D, et al., (2008) Am J Pathol. 173(1):130-43

Additional Info

Recognizes human CHI3L1.

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